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Article

Depletion of a novel SET-domain protein enhances the sterility of mes-3 and mes-4 mutants of Caenorhabditis elegans.

Genetics - 1 Nov 2001

Xu L, Strome S

Abstract excerpt

Four maternal-effect sterile genes, mes-2, mes-3, mes-4, and mes-6, are essential for germline development in Caenorhabditis elegans. Homozygous mes progeny from heterozygous mothers are themselves fertile but produce sterile progeny with underproliferated and degenerated germlines. All four mes genes encode chromatin-associated proteins, two of which resemble known regulators of gene expression. To identify...

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Identifiers

PMID: 11729150
DOI: 10.1093/genetics/159.3.1019
PMCID: PMC1461883

Genes

SET

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Depletion of a novel SET-domain protein enhances the sterility of mes-3 and mes-4 mutants of Caenorhabditis elegans.PMID 11729150Read ↗

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