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Article

Heterogeneous genetic alterations in ovarian mucinous tumors: application and usefulness of laser capture microdissection.

Human pathology - 1 Nov 2001

Takeshima Y, Amatya V J, Daimaru Y, Nakayori F, Nakano T, Inai K

Abstract excerpt

Histologic observation of ovarian mucinous tumors suggests that there is a multistep transition through the accumulation of genetic alterations. We analyzed loss of heterozygosity (LOH) and replication error (RER) on TP53 and D17S855 as well as K-ras point mutations of the heterogeneous histologic areas of the same tumor in 26 cases of ovarian mucinous tumor. The laser capture microdissection (LCM) technique has...

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PMID: 11727259
DOI: 10.1053/hupa.2001.28956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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