Article
Apolipoprotein E phenotype regulates cholesterol absorption in healthy 13-month-old children--The STRIP Study.
Pediatric research - 1 Dec 2001
Tammi A, Rönnemaa T, Rask-Nissilä L, Miettinen T A, Gylling H, Valsta L, Viikari J, Välimäki I, Simell O
Abstract excerpt
High serum cholesterol concentration is one of the key risk factors in development of atherosclerosis, which may begin early in life and later progress to symptomatic coronary heart disease. In adults, apoE polymorphism strongly influences cholesterol metabolism, as subjects with apoE 3/4 or 4/4 (collectively called apoE4) phenotype absorb cholesterol effectively and thus also have higher cholesterol...
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