Article
Stanol ester margarine alone and with simvastatin lowers serum cholesterol in families with familial hypercholesterolemia caused by the FH-North Karelia mutation.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2000
Vuorio A F, Gylling H, Turtola H, Kontula K, Ketonen P, Miettinen T A
Abstract excerpt
In heterozygous familial hypercholesterolemia (FH), serum low density lipoprotein (LDL) cholesterol levels are already elevated at birth. Premature coronary heart disease occurs in approximately 30% of heterozygous untreated adult patients. Accordingly, to retard development of atherosclerosis, preventive measures for lowering cholesterol should be started even in childhood. To this end, 19 FH families consumed...
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