Article
Apolipoprotein E polymorphism and serum lipids in a randomized, prospective trial of an infant diet with reduced saturated fat and cholesterol.
Pediatrics - 1 Oct 1996
Lapinleimu H, Viikari J, Rönnemaa T, Välimäki I, Tuominen J, Marniemi J, Ehnholm C, Jokinen E, Simell O
Abstract excerpt
BACKGROUND: The inherited apolipoprotein E (apoE) phenotype may determine effectiveness of dietary atherosclerosis prevention. This study analyzes the effects of apoE phenotypes on changes in serum lipid concentrations in a 6-month prospective, randomized trial of a low-saturated-fat, low-cholesterol diet in infancy. PATIENTS AND METHODS: One thousand sixty-two healthy infants were randomized to intervention and...
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