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Article

Molecular pathogenesis of pancreatic ductal adenocarcinoma and clinical implications.

Surgical oncology - 1 Jan 2000

Magee C J, Greenhalf W, Howes N, Ghaneh P, Neoptolemos J P

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is a significant cause of cancer death worldwide. PDAC is also one of the best-studied cancers with regard to molecular pathogenesis. The chief risk factors associated with PDAC are smoking and pancreatitis, in addition genetic predisposition seems to play a major role. This genetic predisposition may in some cases be indirect, for example via the elevated risk of...

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PMID: 11719025
DOI: 10.1016/s0960-7404(01)00016-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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