Article
Diminished corneal angiogenesis in gelatinase A-deficient mice.
FEBS letters - 16 Nov 2001
Kato T, Kure T, Chang J H, Gabison E E, Itoh T, Itohara S, Azar D T
Abstract excerpt
The goal of the present study was to define the role of gelatinase A in angiogenesis. We performed corneal micropocket assays in gelatinase A-deficient mice and their age-matched wild-type littermates. The corneal neovascular area in gelatinase A-deficient mice (0.15+/-0.14 mm(2)) was significantly less than that of wild-type littermates (0.53+/-0.35 mm(2); P<0.01). Similarly, aortic ring assays showed...
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