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Article

Zonadhesin: Characterization, Localization, and Zona Pellucida Binding1

1 Dec 2001

Abstract excerpt

Zonadhesin is a multiple-domain transmembrane protein that is believed to function as a sperm-zona pellucida binding protein. In this study we sequenced zonadhesin from rabbit testis and analyzed its processing, expression, localization, and zona pellucida binding. We show that the precursor protein occurs exclusively in the testis and that proteolytic processing results in the formation of three fragments: p43...

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PMID: 11717130
DOI: 10.1095/biolreprod65.6.1691

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