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Mapping Full-Length Porcine Endogenous Retroviruses in a Large White Pig

15 Dec 2001

Abstract excerpt

Xenotransplantation may bridge the widening gap between the shortage of donor organs and the increasing number of patients waiting for transplantation. However, a major safety issue is the potential cross-species transmission of porcine endogenous retroviruses (PERV). This problem could be resolved if it is possible to produce pigs that do not contain replication-competent copies of this virus. In order to...

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PMID: 11711616
DOI: 10.1128/jvi.75.24.12252-12265.2001

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