Article
Effects of intracellular glutathione on sensitivity of Escherichia coli to mercury and arsenite.
Biochemical and biophysical research communications - 6 Jan 1998
Latinwo L M, Donald C, Ikediobi C, Silver S
Abstract excerpt
The effect of intracellular glutathione on sensitivity to mercuric cations and arsenite anions was studied in Escherichia coli mutants that lack glutathione (gshA) with or without an additional mutation affecting the osmotregulant trehalose. The absence of glutathione increased cellular sensitivity to both Hg2+ and AsO2-. The double mutant was more sensitive to Hg2+ than the single mutant strain. The addition of...
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