Article
EWI-2 modulates lymphocyte integrin alpha4beta1 functions.
Blood - 15 Apr 2004
Kolesnikova Tatiana V, Stipp Christopher S, Rao Ravi M, Lane William S, Luscinskas Francis W, Hemler Martin E
Abstract excerpt
The most prominent cell-surface integrin alpha4beta1 partner, a 70-kDa protein, was isolated from MOLT-4 T leukemia cells, using anti-alpha4beta1 integrin antibody-coated beads. By mass spectrometry, this protein was identified as EWI-2, a previously described cell-surface partner for tetraspanin proteins CD9 and CD81. Wild-type EWI-2 overexpression had no effect on MOLT-4 cell tethering and adhesion...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
