Article
Frameshift-mutation-derived peptides as tumor-specific antigens in inherited and spontaneous colorectal cancer.
Proceedings of the National Academy of Sciences of the United States of America - 6 Nov 2001
Saeterdal I, Bjørheim J, Lislerud K, Gjertsen M K, Bukholm I K, Olsen O C, Nesland J M, Eriksen J A, Møller M, Lindblom A, Gaudernack G
Abstract excerpt
The functional role and specificity of tumor infiltrating lymphocytes (TIL) is generally not well characterized. Prominent lymphocyte infiltration is the hallmark of the most common form of hereditary colon cancer, hereditary nonpolyposis colon cancer (HNPCC) and the corresponding spontaneous colon cancers with the microsatellite instability (MSI) phenotype. These cancers are caused by inherited or acquired...
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