Article
Detection and isolation of minisatellite Pc-1 binding proteins.
Biochimica et biophysica acta - 3 Oct 2001
Fukuda H, Sugimura T, Nagao M, Nakagama H
Abstract excerpt
Minisatellites (MNs) are arrays of 5-100 nucleotide repeats that are dispersed throughout the genome of vertebrates. They demonstrate alteration in tumors and in cells exposed to various carcinogens, but the molecular mechanisms underlying the induction of mutations at MNs are largely unknown. Hypervariable MN Pc-1 isolated from the mouse genome consists of tandem repeats of d(GGCAG) flanked with locus-specific...
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