Article
Intramolecular quadruplex formation of the G-rich strand of the mouse hypervariable minisatellite Pc-1.
Biochemical and biophysical research communications - 22 Oct 1999
Katahira M, Fukuda H, Kawasumi H, Sugimura T, Nakagama H, Nagao M
Abstract excerpt
The minisatellite Pc-1, isolated from the mouse genome consisting of a tandem repeat of d(GGCAG), is hypervariable with a mutation rate of 0.15/generation. Here we describe a structural characterization of the G-rich strand of Pc-1 by biochemical and physicochemical methods. It was found to be comparatively resistant to both single-stranded DNA-binding protein binding and digestion by single-stranded DNA-specific...
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