Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Peg3/Pw1 Is Involved in p53-mediated Cell Death Pathway in Brain Ischemia/Hypoxia

1 Jan 2002

Abstract excerpt

Emerging evidence has shown that tumor suppressor p53 expression is enhanced in response to brain ischemia/hypoxia and that p53 plays a critical role in the cell death pathway in such an acute neurological insult. However the mechanism remains unclear. Recently it was reported that Peg3/Pw1, originally identified as a paternally expressed gene, plays a pivotal role in the p53-mediated cell death pathway in mouse...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Epigenetics and DNA Methylation
Share to Hedgehog Signaling Pathway Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11679586
DOI: 10.1074/jbc.m107435200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Peg3/Pw1 Is Involved in p53-mediated Cell Death Pathway in Brain Ischemia/HypoxiaPMID 11679586Read ↗

P53 protein and the diseases in central nervous systemSemantic proximity Read ↗

ATF2/BAP1 Axis Mediates Neuronal Apoptosis After Subarachnoid Hemorrhage via P53 PathwaySemantic proximity Read ↗

Nuclear localization of the hypoxia-regulated pro-apoptotic protein BNIP3 after global brain ischemia in the rat hippocampusSemantic proximity Read ↗

Identification of a Novel Hypoxia-Inducible Factor 1-Responsive Gene, <i>RTP801</i> , Involved in ApoptosisSemantic proximity Read ↗

Differential effect of ik3-1/cables on p53- and p73-induced cell death.Semantic proximity Read ↗

Long non-coding RNA MEG3 alters neuronal apoptosis and is associated with poor prognosis in ischemic stroke: based on basic and prospective studiesSemantic proximity Read ↗

A Glance of p53 Functions in Brain Development, Neural Stem Cells, and Brain CancerSemantic proximity Read ↗

p53 in neurodegenerative diseases and brain cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.