Article
The global posttranscriptional regulator RsmA modulates production of virulence determinants and N-acylhomoserine lactones in Pseudomonas aeruginosa.
Journal of bacteriology - 1 Nov 2001
Pessi G, Williams F, Hindle Z, Heurlier K, Holden M T, Cámara M, Haas D, Williams P
Abstract excerpt
Posttranscriptional control is known to contribute to the regulation of secondary metabolism and virulence determinants in certain gram-negative bacteria. Here we report the isolation of a Pseudomonas aeruginosa gene which encodes a global translational regulatory protein, RsmA (regulator of secondary metabolites). Overexpression of rsmA resulted in a substantial reduction in the levels of extracellular products,...
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