Article
Two GacA-dependent small RNAs modulate the quorum-sensing response in Pseudomonas aeruginosa.
Journal of bacteriology - 1 Aug 2006
Kay Elisabeth, Humair Bérénice, Dénervaud Valérie, Riedel Kathrin, Spahr Stéphanie, Eberl Leo, Valverde Claudio, Haas Dieter
Abstract excerpt
In Pseudomonas aeruginosa, the GacS/GacA two-component system positively controls the quorum-sensing machinery and the expression of extracellular products via two small regulatory RNAs, RsmY and RsmZ. An rsmY rsmZ double mutant and a gacA mutant were similarly impaired in the synthesis of the quorum-sensing signal N-butanoyl-homoserine lactone, the disulfide bond-forming enzyme DsbA, and the exoproducts hydrogen...
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