Article
NFkappaB polymorphisms and susceptibility to type 1 diabetes.
Genes and immunity - 1 Oct 2001
Hegazy D M, O'Reilly D A, Yang B M, Hodgkinson A D, Millward B A, Demaine A G
Abstract excerpt
Nuclear factor kappa B (NFkappaB) is an important transcription factor that is involved in the response to oxidative stress and inflammation. Recent studies suggest that it may be involved in the development of diabetic microvascular complications. A highly polymorphic (CA) dinucleotide repeat microsatellite has been identified in the regulatory region of the NFkappaB gene. The aim of this study was to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
