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Article

Genetic instability and the evolution of angiogenic tumor cell lines (review).

Oncology reports - 1 Jan 2000

Wodarz D, Krakauer D C

Abstract excerpt

Advanced tumor growth requires the formation of new blood vessels (angiogenesis). Whether new blood vessels are formed or not depends on a balance between angiogenesis inhibitors and promoters. Host tissue, as well as tumor cells, express inhibitory factors preventing angiogenesis. During cancer progression, tumor cell lines evolve which produce factors promoting the angiogenic switch. We use mathematical models...

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Identifiers

PMID: 11605033
DOI: 10.3892/or.8.6.1195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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