Article
Phosphatidylethanolamine has an essential role in Saccharomyces cerevisiae that is independent of its ability to form hexagonal phase structures.
The Journal of biological chemistry - 21 Dec 2001
Storey M K, Clay K L, Kutateladze T, Murphy R C, Overduin M, Voelker D R
Abstract excerpt
Two yeast enzymes, Psd1p and Psd2p, catalyze the decarboxylation of phosphatidylserine to produce phosphatidylethanolamine (PtdEtn). Mitochondrial Psd1p provides approximately 90% of total cellular phosphatidylserine decarboxylase activity. When the PSD1 gene is deleted, the resultant strain (psd1Delta) grows normally at 30 degrees C in glucose and in the absence of exogenous choline or ethanolamine. However, at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.