Article
Non-invasive observation of repeated adenoviral GFP gene delivery to the anterior segment of the monkey eyein vivo
1 Jan 2001
Abstract excerpt
BACKGROUND: Glaucoma is a group of chronic eye diseases often associated with an elevated intraocular pressure (IOP). If not controlled, the condition leads to blindness. The eye tissue responsible for maintaining aqueous humor resistance and thus normal IOP is the trabecular meshwork (TM). Adenoviral vectors are capable of transducing the TM in several rodent species. Because of the relevance of the non-human...
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