Article
Monocyte activation and differentiation augment human endogenous retrovirus expression: implications for inflammatory brain diseases.
Annals of neurology - 1 Oct 2001
Johnston J B, Silva C, Holden J, Warren K G, Clark A W, Power C
Abstract excerpt
Human endogenous retroviruses (HERVs) have been implicated as causative agents in diseases characterized by inflammation and macrophage activation, such as multiple sclerosis. Because monocyte activation and differentiation influence retroviral transcription and replication, we investigated the contribution of these processes to the expression of four HERV families (HERV-W, HERV-K, HERV-E, and HERV-H) in human...
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