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Article

Analysis of <i>iceA </i>genotypes in South African <i>Helicobacter pylori</i> strains and relationship to clinically significant disease

1 Nov 2001

Abstract excerpt

BACKGROUND: South African Helicobacter pylori isolates are characterised by the universal presence of cagA but have differences in vacuolating cytotoxin gene (vacA) alleles which correlate with clinically significant disease. However, the candidate virulence marker gene iceA has not been investigated. AIM: To characterise the genetic organisation and heterogeneity of iceA genotypes in different South African...

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PMID: 11600464
DOI: 10.1136/gut.49.5.629

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