Article
Comparative genomics of Helicobacter pylori isolates recovered from ulcer disease patients in England.
BMC microbiology - 25 May 2005
Kauser Farhana, Hussain M Abid, Ahmed Irshad, Srinivas Sriramula, Devi S Manjulata, Majeed Ahmed A, Rao K Rajender, Khan Aleem A, Sechi Leonardo A, Ahmed Niyaz
Abstract excerpt
BACKGROUND: Genomic diversity of H. pylori from many different human populations is largely unknown. We compared genomes of 65 H. pylori strains from Nottingham, England. Molecular analysis was carried out to identify rearrangements within and outside the cag-pathogenicity-island (cag PAI) and DNA sequence divergence in candidate genes. Phylogenetic analysis was carried out based on various high-resolution...
Topics
- Bacterial Proteins
- England
- Genetic Variation
- Genome, Bacterial
- Genomics
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Phylogeny
- Stomach Ulcer
- Virulence Factors