Article
Helicobacter pylori patient isolates from South Africa and Nigeria differ in virulence factor pathogenicity profile and associated gastric disease outcome.
Scientific reports - 10 Jul 2020
Palamides Pia, Jolaiya Tolulope, Idowu Ayodeji, Loell Eva, Onyekwere Charles, Ugiagbe Rose, Agbo Ifeanyi, Lesi Olufunmilayo, Ndububa Dennis, Adekanle Olusegun, Carranza Manuel, Ally Reidwaan, Njom Henry, Adeleye Isaac A, Harrison Ute, Clarke Anna, Fischer Wolfgang, Smith Stella, Haas Rainer
Abstract excerpt
Helicobacter pylori is a gram-negative, spiral-shaped bacterial pathogen and the causative agent for gastritis, peptic ulcer disease and classified as a WHO class I carcinogen. While the prevalence of H. pylori infections in Africa is among the highest in the world, the incidence of gastric cancer is comparably low. Little is known about other symptoms related to the H. pylori infection in Africa and the...
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