Article
Prevalence of Helicobacter pylori vacA, cagA and iceA genotypes in South African patients with upper gastrointestinal diseases.
Acta tropica - 1 Oct 2010
Tanih Nicoline F, McMillan Martin, Naidoo Nathan, Ndip Lucy M, Weaver Lawrence T, Ndip Roland N
Abstract excerpt
Clinical response to Helicobacter pylori infection may be determined by specific virulence-associated genotypes which varies geographically. The aim of this study was to investigate the diversity of putative virulence markers of H. pylori; cagA, vacA and iceA in the Eastern Cape Province of South Africa. One hundred H. pylori strains obtained from dyspeptic patients were used. Gastric biopsies were obtained from...
Topics
- Antigens, Bacterial
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Biomarkers
- DNA Primers
- Gastrointestinal Diseases
- Genes, Bacterial
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Polymerase Chain Reaction
- Prevalence
- Rural Population