Article
Molecular genetics of cutaneous lymphomas.
Annals of the New York Academy of Sciences - 1 Sept 2001
Whittaker S
Abstract excerpt
The underlying molecular basis of primary cutaneous lymphomas has not yet been clarified. However, abnormalities of cell cycle control genes and well-defined tumor suppressor genes such as p53 are common and may contribute to disease progression and treatment resistance. Biallelic inactivation of tumor suppressor genes usually occurs by a combination of deletion, point mutation, and/or promotor hypermethylation....
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