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Article

Similar nucleotide excision repair capacity in melanocytes and melanoma cells.

Cancer research - 15 Jun 2010

Gaddameedhi Shobhan, Kemp Michael G, Reardon Joyce T, Shields Janiel M, Smith-Roe Stephanie L, Kaufmann William K, Sancar Aziz

Abstract excerpt

Sunlight UV exposure produces DNA photoproducts in skin that are repaired solely by nucleotide excision repair in humans. A significant fraction of melanomas are thought to result from UV-induced DNA damage that escapes repair; however, little evidence is available about the functional capacity o...

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Source

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Identifiers

PMID: 20501836
DOI: 10.1158/0008-5472.CAN-10-0095
PMCID: PMC2891231

Genes

DDB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20501836-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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