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Article

Nicotinamide enhances repair of ultraviolet radiation‐induced <scp>DNA</scp> damage in primary melanocytes

5 May 2014

Abstract excerpt

Cutaneous melanoma is a significant cause of morbidity and mortality. Nicotinamide is a safe, widely available vitamin that reduces the immune suppressive effects of UV, enhances DNA repair in keratinocytes and has shown promise in the chemoprevention of non-melanoma skin cancer. Here, we report the effect of nicotinamide on DNA damage and repair in primary human melanocytes. Nicotinamide significantly enhanced...

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PMID: 24798949
DOI: 10.1111/exd.12430

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