Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A scytalone dehydratase gene from Ophiostoma floccosum restores the melanization and pathogenicity phenotypes of a melanin-deficient Colletotrichum lagenarium mutant.

Molecular genetics and genomics : MGG - 1 Sept 2001

Wang H L, Kim S H, Breuil C

Abstract excerpt

Scytalone dehydratase is involved in the production of fungal dihydroxynaphthalene (DHN) melanin. We have isolated and characterized OSD1, a gene encoding scytalone dehydratase from the sap-staining fungus Ophiostoma floccosum by PCR-based cloning. Sequence analysis suggests that the OSD1 gene encodes a protein of 216 amino acids with a molecular weight of 24.2 kDa that shows 51-70% sequence identity to other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ascomycota
Share to Blotting, Southern

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Fungal

Share to Genes, Fungal

Share to Genetic Complementation Test

Share to Hydro-Lyases

Share to Melanins

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 11589570
DOI: 10.1007/s004380100534

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A scytalone dehydratase gene from Ophiostoma floccosum restores the melanization and pathogenicity phenotypes of a melanin-deficient Colletotrichum lagenarium mutant.PMID 11589570Read ↗

Biosynthesis and functions of melanin in Sporothrix schenckii.Semantic proximity Read ↗

Evidence for involvement of two naphthol reductases in the first reduction step of melanin biosynthesis pathway of Colletotrichum lagenarium.Semantic proximity Read ↗

Characterization of a Hypovirus-Regulated Septin Cdc11 Ortholog, CpSep1, from the Chestnut Blight Fungus Cryphonectria parasitica.Semantic proximity Read ↗

Agrobacterium-meditated gene disruption using split-marker in Grosmannia clavigera, a mountain pine beetle associated pathogen.Semantic proximity Read ↗

The role of melanin pathways in extremotolerance and virulence ofFonsecaearevealed byde novoassembly transcriptomics using illumina paired-end sequencingSemantic proximity Read ↗

Deficiency of ChPks and ChThr1 Inhibited DHN-melanin Biosysthesis, Disrupted Cell Wall Integrity and Attenuated Pathogenicity in Colletotrichum higginsianumSemantic proximity Read ↗

Compartmentalization of Melanin Biosynthetic Enzymes Contributes to Self-Defense against Intermediate Compound Scytalone in Botrytis cinerea.Semantic proximity Read ↗

LAC2 encoding a secreted laccase is involved in appressorial melanization and conidial pigmentation in Colletotrichum orbiculare.Semantic proximity Read ↗

The thn mutation of Schizophyllum commune, which suppresses formation of aerial hyphae, affects expression of the Sc3 hydrophobin gene.Semantic proximity Read ↗

Characterization of Streptomyces scabies mutants deficient in melanin biosynthesis.Semantic proximity Read ↗

The Alternaria alternata melanin biosynthesis gene restores appressorial melanization and penetration of cellulose membranes in the melanin-deficient albino mutant of Colletotrichum lagenarium.Semantic proximity Read ↗

Heterologous Expression and Product Identification of<i>Colletotrichum lagenarium</i>Polyketide Synthase Encoded by the<i>PKS1</i>Gene Involved in Melanin BiosynthesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.