Article
The role of cytokines and chemokines in the T-cell-mediated autoimmune process in alopecia areata.
Experimental dermatology - 1 Nov 2014
Ito Taisuke, Tokura Yoshiki
Abstract excerpt
The aetiology of alopecia areata (AA) is still not fully understood. However, recent clinical and experimental studies have provided insights into the pathomechanisms of AA and revealed that it is an organ-specific and cell-mediated autoimmune disease. Some triggers, such as viral infections, trauma, hormones and emotional/physical stressors, may cause activation of autoreactive T cells that target hair follicle...
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