Article
Mouse models of cystic fibrosis.
Trends in genetics : TIG - 1 Oct 2001
Davidson D J, Rolfe M
Abstract excerpt
The development of mouse models for cystic fibrosis has provided the opportunity to dissect disease pathogenesis, correlate genotype and phenotype, study disease-modifying genes and develop novel therapeutics. This review discusses the successes and the challenges encountered in characterizing and optimizing these models.
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