Article
Regional and hormone-dependent effects of apolipoprotein E genotype on changes in bone mineral in perimenopausal women.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Oct 2001
Gerdes L U, Vestergaard P, Hermann A P, Mosekilde L
Abstract excerpt
We studied 479 perimenopausal Danish women aged 45-58 years to examine differences between APOE genotypes with respect to (1) baseline total body bone mineral density (BMD) and densities measured in five different regions (ultradistal forearm, proximal forearm, lumbar spine, femoral neck, and total hip region); (2) serum levels of alkaline phosphatase, bone isoenzyme alkaline phosphatase, osteocalcin, parathyroid...
Topics
- Alkaline Phosphatase
- Apolipoprotein E2
- Apolipoprotein E3
- Apolipoprotein E4
- Apolipoproteins E
- Biomarkers
- Bone Density
- Bone and Bones
- Climacteric
- Denmark
- Female
- Follow-Up Studies
- Genotype
- Hormone Replacement Therapy