Article
Molecular indexing of human genomic DNA.
Nucleic acids research - 1 Oct 2001
Sibson D R, Gibbs F E
Abstract excerpt
Molecular indexing sorts DNA fragments into subsets for inter-sample comparisons. Type IIS or interrupted palindrome restriction endonucleases, which result in single-stranded ends not including the original recognition sequence of the enzyme, are used to produce the fragments. The ends can then be any sequence but will always be specific for a given fragment. Fragments with particular ends are selected by...
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