Article
Behavioral and physiological effects of biotechnology procedures used for gene targeting in mice.
Physiology & behavior - 1 Aug 2001
Van der Meer M, Baumans V, Olivier B, Kruitwagen C L, Van Dijk J E, Van Zutphen L F
Abstract excerpt
The effects of gene-targeting procedures on the behavior and physiological development of (chimeric) mice have been investigated. We used six groups of mice, each of them undergoing specific aspects of the biotechnological procedure, including electroporation, microinjection, and/or blastocyst culture. Changes in behavior and physiological development of the progeny (age 4-30 weeks) were investigated. Besides...
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