Article
[Transgenic mammals in the biology of development].
Ontogenez - 1 Jan 2000
Dyban A P
Abstract excerpt
Cells and chromosomes of the embryo can be labeled by integrating foreign DNA into its genome. Genes coding for some cytotoxic products can selectively destroy embryonic rudiments in which these genes are expressed. Insertional mutations arise in transgenic animals and this facilitates identification and cloning of the genes that affect the development. Embryos carrying mutations in certain genes were produced...
Topics
- Animals
- Animals, Genetically Modified
- Cloning, Molecular
- DNA
- Gene Expression
- Genetic Markers
- Growth
- Mutation
- Transfection