Article
Absorption and disposition of levocetirizine, the eutomer of cetirizine, administered alone or as cetirizine to healthy volunteers.
Fundamental & clinical pharmacology - 1 Aug 2001
Baltes E, Coupez R, Giezek H, Voss G, Meyerhoff C, Strolin Benedetti M
Abstract excerpt
The primary objective of the present study was to compare the absorption and disposition of levocetirizine, the eutomer of cetirizine, when administered alone (10 mg) or in presence of the distomer. An additional objective was also to investigate the configurational stability of levocetirizine in vivo in humans. The study was performed in a randomized, two-way cross-over, single-dose design with a wash-out phase...
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