Article
An improved method for quantitative trait loci detection and identification of within-line segregation in F2 intercross designs.
Genetics - 1 Apr 2008
Rönnegård Lars, Besnier Francois, Carlborg Orjan
Abstract excerpt
We present a new flexible, simple, and powerful genome-scan method (flexible intercross analysis, FIA) for detecting quantitative trait loci (QTL) in experimental line crosses. The method is based on a pure random-effects model that simultaneously models between- and within-line QTL variation for single as well as epistatic QTL. It utilizes the score statistic and thereby facilitates computationally efficient...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
