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Article

Altered expression of beta-catenin without genetic mutation in intrahepatic cholangiocarcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2001

Sugimachi K, Taguchi K, Aishima S, Tanaka S, Shimada M, Kajiyama K, Sugimachi K, Tsuneyoshi M

Abstract excerpt

beta-catenin which has a role in E-cadherin mediated cell-to-cell adhesion, and is also involved in Wnt signaling pathways as a downstream signaling molecule accumulating in the cytoplasm and nucleus constitutively activates Tcf/LEF-associated transcription of oncogenic genes. We examined the expression pattern and the genetic alteration of beta-catenin to determine the role of beta-catenin in cancer formation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bile Ducts, Intrahepatic

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Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 11557787
DOI: 10.1038/modpathol.3880409

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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