Article
Heterogeneity of Helicobacter pylori cag genotypes in experimentally infected mice.
FEMS microbiology letters - 11 Sept 2001
Sozzi M, Crosatti M, Kim S K, Romero J, Blaser M J
Abstract excerpt
Our aim was to assess whether the Helicobacter pylori population recovered from experimentally infected mice show heterogeneity in cag genotypes. Wild-type FVB/N mice were challenged with strain Hp1 and sacrificed 8 weeks later. Direct PCR on gastric tissue was performed using primers for glmM and cagA, and for these two genes and for cagE and virB11 using DNA from the infecting and the emerging strains. The...
Topics
- Animals
- Antigens, Bacterial
- Bacterial Proteins
- Disease Models, Animal
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Mice
- Phosphoglucomutase