Article
Individual hosts carry H. pylori isolates with different cagA features - motifs and copy number.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2021
Saniee Parastoo, Jalili Shiva, Ghadersoltani Paria, Daliri Layegheh, Siavoshi Farideh
Abstract excerpt
BACKGROUND: H. pylori strains with different genetic contents may infect different or an individual human host. Genetic diversity of cagA is thought to contribute to differences in H. pylori strains pathogenicity. In this study, diversity of cagA genotype, EPIYA motif and copy number was assessed in H. pylori single colonies isolated from individual patients. MATERIALS AND METHODS: Gastric biopsies from 14H....
Topics
- Adult
- Aged
- Aged, 80 and over
- Antigens, Bacterial
- Bacterial Proteins
- DNA Copy Number Variations
- Female
- Genotype
- Helicobacter Infections
- Helicobacter pylori