Article
Slow genetic divergence of Helicobacter pylori strains during long-term colonization.
Infection and immunity - 1 Aug 2005
Lundin Annelie, Björkholm Britta, Kupershmidt Ilya, Unemo Magnus, Nilsson Peter, Andersson Dan I, Engstrand Lars
Abstract excerpt
The genetic variability of Helicobacter pylori is known to be high compared to that of many other bacterial species. H. pylori is adapted to the human stomach, where it persists for decades, and adaptation to each host results in every individual harboring a distinctive bacterial population. Although clonal variants may exist within such a population, all isolates are generally genetically related and thus...
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