Article
The nucleotide sequence of two new DP alleles, DPA1*02015 and DPB1*8401, identified in a Chinese subject.
Tissue antigens - 1 Jul 2000
McTernan C L, Mijovic C H, Cockram C S, Barnett A H
Abstract excerpt
The HLA-DP genes (HLA-DPA1 and -DPB1) are encoded by the major histocompatibility complex (MHC) on human chromosome 6. They are involved in the presentation of antigen to CD4+ T cells as part of the class II antigen-presentation pathway. During a small study of Oriental subjects (11 Chinese and 26 Japanese subjects), one Chinese subject was identified as having numerous heterozygous sites within the second exon...
Topics
- Alleles
- Base Sequence
- China
- HLA-DP Antigens
- HLA-DP alpha-Chains
- HLA-DP beta-Chains
- Humans
- Molecular Sequence Data
- Polymorphism, Genetic
- Sequence Alignment
