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Article

Telomere maintenance by telomerase and by recombination can coexist in human cells

1 Sept 2001

Abstract excerpt

Immortal human cells maintain their telomeres by two independent mechanisms, a prevalent one dependent on de novo synthesis of telomeric DNA by telomerase, and a rarer one based on telomere recombination [alternative lengthening of telomeres (ALT)]. Studies with yeast have indicated that expression of telomerase inhibits telomere recombination. In the present study, we have investigated whether expression of...

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Identifiers

PMID: 11555631
DOI: 10.1093/hmg/10.18.1945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Telomere maintenance by telomerase and by recombination can coexist in human cellsPMID 11555631Read ↗

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