Article
Domain structure and conserved epitopes of Sfb protein, the fibronectin‐binding adhesin of <i>Streptococcus pyogenes</i>
1 Aug 1994
Abstract excerpt
Streptococcus pyogenes expresses a fibronectin-binding surface protein (Sfb protein) which mediates adherence to human epithelial cells. The nucleotide sequence of the sfb gene was determined and the primary sequence of the Sfb protein was analysed. The protein consists of 638 amino acids and comprises five structurally distinct domains. The protein starts with an N-terminal signal peptide followed by an aromatic...
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