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Article

Ligation of CD40 stimulates the induction of nitric-oxide synthase in microglial cells.

The Journal of biological chemistry - 30 Nov 2001

Jana M, Liu X, Koka S, Ghosh S, Petro T M, Pahan K

Abstract excerpt

The present study was undertaken to investigate the role of CD40 ligation in the expression of inducible nitric-oxide synthase (iNOS) in mouse BV-2 microglial cells and primary microglia. Ligation of CD40 alone by either cross-linking antibodies against CD40 or a recombinant CD40 ligand (CD154) was unable to induce the production of NO in BV-2 microglial cells. The absence of induction of NO production by CD40...

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Identifiers

PMID: 11551948
DOI: 10.1074/jbc.M106771200
PMCID: PMC2041871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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