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Article

PAX3-FKHR induces morphological change and enhances cellular proliferation and invasion in rhabdomyosarcoma.

The American journal of pathology - 1 Sept 2001

Anderson J, Ramsay A, Gould S, Pritchard-Jones K

Abstract excerpt

Alveolar rhabdomyosarcoma (ARMS) is consistently associated with the characteristic translocations t(2;13)(q35;q14) and t(1;13)(p36;q14), which encode for the PAX3-FKHR and PAX7-FKHR fusion oncoproteins respectively. We have investigated the relationship between PAX3-FKHR expression and ARMS hist...

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Source

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Identifiers

PMID: 11549601
DOI: 10.1016/S0002-9440(10)61784-1
PMCID: PMC1850440

Genes

PAX3
PAX7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11549601-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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