Article
Antiphospholipid antibodies and the endothelium.
Rheumatic diseases clinics of North America - 1 Aug 2001
Meroni P L, Raschi E, Testoni C, Tincani A, Balestrieri G
Abstract excerpt
The interaction between aPL (particularly anti-beta 2GPI antibodies) and endothelium does represent a potential pathogenetic mechanism for the thrombotic manifestations of the syndrome. The autoantibody-mediated EC activation probably plays a role in sustaining the appearance of a proadhesive, proinflammatory, and procoagulant phenotype. The heterogeneity of the APS clinical manifestations is likely linked to the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
