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Article

Pathogenesis of the Antiphospholipid Syndrome

17 Apr 2012

Abstract excerpt

The presence of pathogenic antiphospholipid antibodies (aPL) is the characterizing feature of the antiphospholipid syndrome (APS), mediating the recurrent pregnancy loss and thrombosis typical of the disease, through their action on various antigenic targets. Despite the available knowledge regarding the mechanisms by which aPL induce a procoagulant phenotype in the vasculature and abnormal cellular proliferation...

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PMID: 22510982
DOI: 10.1055/s-0032-1311827

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