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Article

UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish.

Science (New York, N.Y.) - 31 Aug 2001

Walsh E C, Stainier D Y

Abstract excerpt

Cardiac valve formation is a complex process that involves cell signaling events between the myocardial and endocardial layers of the heart across an elaborate extracellular matrix. These signals lead to marked morphogenetic movements and transdifferentiation of the endocardial cells at chamber boundaries. Here we identify the genetic defect in zebrafish jekyll mutants, which are deficient in the initiation of...

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Identifiers

PMID: 11533493
DOI: 10.1126/science.293.5535.1670

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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